How does a cell anchor and invade an organ?

Abstract

In multicellular organisms, most cells are confined to a particular tissue. However, some cells invade organs during normal development and in diseases (e.g., angiogenesis and cancer). Recent studies reveal a fascinating step-by-step process in which specific vulval cells induce and attract a single gonadal cell to invade an epithelial tubular organ in order to connect the uterus to the vulva in C. elegans.