Synthesis and antibacterial properties of 4-sulfonamidopyrimidine derivatives

Jerzy Cieplik; Janusz Pluta; Olaf Gubrynowicz

Synthesis and antibacterial properties of 4-sulfonamidopyrimidine derivatives

Acta Pol Pharm. 2003 Jan-Feb;60(1):75-9.

Authors

Jerzy Cieplik¹, Janusz Pluta, Olaf Gubrynowicz

Affiliation

¹ Department of Organic Chemistry, Medical Academy, 9 Grodzka Str., 50-137 Wrocław, Poland.

PMID: 12848371

Abstract

The synthesis of derivatives of 4-aryl-6-methyl-sulfonamido-2-phenyl-5-carboxypyrimidine acid was presented and antibacterial activity of the obtained compounds was investigated.

MeSH terms

Anti-Bacterial Agents / chemical synthesis*
Anti-Bacterial Agents / pharmacology*
Bacteria / drug effects*
Chemical Phenomena
Chemistry, Physical
Indicators and Reagents
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Pyrimidines / chemical synthesis*
Pyrimidines / pharmacology*
Sulfonamides / chemical synthesis*
Sulfonamides / pharmacology*

Substances

4-sulfonamidopyrimidine
Anti-Bacterial Agents
Indicators and Reagents
Pyrimidines
Sulfonamides