New taxane diterpenoids from Taiwanese Taxus sumatrana

Chem Pharm Bull (Tokyo). 2003 Jul;51(7):867-9. doi: 10.1248/cpb.51.867.

Abstract

Two new taxane diterpenoids, tasumatrols A (1) and B (2), have been isolated from extracts of the leaves and twigs of Taiwanese Taxus sumatrana. Tasumatrol A is a rare 5/6/6 taxene system, having a novel gamma-lactone at C-10 and C-19. The structures of compounds 1 and 2 were determined on the basis of two dimensional (2D)-NMR techniques, including correlation spectroscopy (COSY), 1H-detected heteronuclear multiple quantum coherence (HMQC) and heteronuclear multiple bond connectivity (HMBC) experiments.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bridged-Ring Compounds / chemistry
  • Bridged-Ring Compounds / isolation & purification*
  • Diterpenes / chemistry
  • Diterpenes / isolation & purification*
  • Plant Extracts / chemistry
  • Plant Extracts / isolation & purification
  • Plant Leaves
  • Plant Stems
  • Taiwan
  • Taxoids / chemistry
  • Taxoids / isolation & purification*
  • Taxus*

Substances

  • Bridged-Ring Compounds
  • Diterpenes
  • Plant Extracts
  • Taxoids
  • taxane