Abstract
Carbapenem-resistant Acinetobacter baumannii isolates were obtained from eight patients in two hospitals in Curitiba, Brazil. The isolates were multiresistant, belonged to a single strain, and produced the OXA-23 carbapenemase. Treatment options were limited, although the isolates were susceptible to polymyxin B in vitro. The strain contributed to the deaths of five patients.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acinetobacter Infections / epidemiology*
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Acinetobacter Infections / microbiology
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Acinetobacter baumannii / drug effects*
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Acinetobacter baumannii / enzymology
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Adult
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Aged
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Aged, 80 and over
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Brazil / epidemiology
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Carbapenems / pharmacology*
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Disease Outbreaks*
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Drug Resistance, Bacterial*
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Hospitals, Teaching
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Humans
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Microbial Sensitivity Tests
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Middle Aged
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beta-Lactamases / metabolism*
Substances
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Carbapenems
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beta-lactamase OXA-23
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beta-Lactamases