Abstract
To further evaluate recombinant Em18 antigen (rEm18) for immunodiagnosis of human alveolar echinococcosis, 208 serum samples were examined by enzyme-linked immunosorbent assay (ELISA). To comparatively assess the results of rEm18-ELISA, ELISA and immunoblot analysis with two affinity-purified native antigens were also performed with 45 selected serum samples. The results indicate that rEm18 is highly useful for serodiagnosis.
Publication types
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Comparative Study
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Evaluation Study
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Antibodies, Helminth / blood*
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Antigens, Helminth / genetics
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Antigens, Helminth / immunology*
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Chromatography, Affinity
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Echinococcosis / diagnosis
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Echinococcosis / parasitology*
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Echinococcosis, Hepatic / diagnosis
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Echinococcosis, Hepatic / parasitology
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Echinococcus / immunology*
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Enzyme-Linked Immunosorbent Assay
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Humans
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Immunoblotting
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Recombinant Proteins / immunology
Substances
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Antibodies, Helminth
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Antigens, Helminth
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Em18 antigen
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Recombinant Proteins