Fatal nucleoside-associated lactic acidosis in an obese woman with human immunodeficiency virus type 1 infection on a very low-calorie diet

Scand J Infect Dis. 2003;35(4):291-3. doi: 10.1080/00365540310004054.

Abstract

This study reports the case of an obese woman with human immunodeficiency virus type 1 (HIV-1) infection who developed fatal nucleoside-associated lactic acidosis 10 d after she started a weight-loss dietary regimen containing 600 kcal/d. This case suggests that very low-calorie diets may be life threatening for HIV-infected patients receiving nucleoside analogues.

Publication types

  • Case Reports

MeSH terms

  • Acidosis, Lactic / complications*
  • Acidosis, Lactic / diagnosis
  • Adult
  • Anti-HIV Agents / administration & dosage
  • Autopsy
  • Diet, Fat-Restricted / adverse effects*
  • Fatal Outcome
  • Female
  • HIV Infections / complications*
  • HIV Infections / diagnosis
  • HIV Infections / drug therapy
  • HIV-1 / isolation & purification*
  • Humans
  • Liver / pathology
  • Obesity / complications
  • Obesity / diagnosis
  • Obesity / diet therapy*
  • Risk Assessment
  • Weight Loss

Substances

  • Anti-HIV Agents