Abstract
We describe a case of poliomyelitis in a 3-year-old Argentinean boy with X-linked hypogammaglobulinemia. The child had no history of polio vaccination, but a poliovirus isolated from a stool sample had 97.2% genetic similarity to the Sabin 1 vaccine strain. According to the WHO definition, this is the first case reported of a vaccine-derived poliovirus infection recorded in continental Latin America.
MeSH terms
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Agammaglobulinemia / immunology*
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Child, Preschool
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Feces / virology
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Follow-Up Studies
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Humans
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Immunocompromised Host*
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Latin America
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Male
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Paralysis / diagnosis
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Paralysis / etiology
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Poliomyelitis / diagnosis
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Poliomyelitis / etiology*
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Poliovirus / isolation & purification*
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Poliovirus Vaccine, Oral / administration & dosage
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Poliovirus Vaccine, Oral / adverse effects*
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Risk Assessment
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Vaccination / adverse effects