Presence of the Tet M determinant in a clinical isolate of Acinetobacter baumannii

Antimicrob Agents Chemother. 2003 Jul;47(7):2310-2. doi: 10.1128/AAC.47.7.2310-2312.2003.

Abstract

The tet(M) gene encodes a protein which is related to tetracycline ribosomal protection, one of the mechanisms of tetracycline resistance. A tet(M) gene that is 100% homologous to the tet(M) gene of Staphylococcus aureus has been found in a clinical isolate of Acinetobacter baumannii, which also carries the tet(A) gene encoding a tetracycline efflux pump.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter / drug effects
  • Acinetobacter / genetics*
  • Anti-Bacterial Agents / pharmacology
  • Bacterial Proteins / genetics*
  • Genes, Bacterial
  • Microbial Sensitivity Tests
  • Minocycline / pharmacology
  • Molecular Sequence Data
  • Staphylococcus aureus / genetics
  • Tetracycline / pharmacology
  • Tetracycline Resistance / genetics*

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Tet M resistance protein, Bacteria
  • Tetracycline
  • Minocycline

Associated data

  • GENBANK/AP003359