It is very important to grasp the artificial heart condition and the physiologic conditions for the implantable artificial heart. In our laboratory, a smart artificial heart (SAH) has been proposed and developed. An SAH is an artificial heart with a noninvasive sensor; it is a sensorized and intelligent artificial heart for safe and effective treatment. In this study, the following sensor systems for SAH are described: noninvasive blood temperature sensor system, noninvasive blood pressure sensor system, and noninvasive small blood flow sensor system. These noninvasive sensor systems are integrated and included around the artificial heart to evaluate these sensor systems for SAH by the mockup experiments and the animal experiments. The blood temperature could be measured stably by the temperature sensor system. Aortic pressure was estimated, and sucking condition was detected by the pressure sensor system. The blood flow was measured by the flow meter system within 10% error. As a result of these experiments, we confirmed the effectiveness of the sensor systems for SAH.