Capillary haemangioma of the eyelids and orbit: a clinical review of the safety and efficacy of intralesional steroid

Acta Ophthalmol Scand. 2003 Jun;81(3):294-8. doi: 10.1034/j.1600-0420.2003.00058.x.

Abstract

Purpose: To describe the presenting features, investigations, treatment and outcome of a series of patients with capillary haemangioma of the eyelids and orbit.

Methods: A retrospective analysis of 21 patients, presenting between the years 1985 and 2000. Effectiveness of treatment was determined by final visual acuity and cosmetic result.

Results: Lesions were more common in females and the upper eyelid was a definite site of predilection. A total of 87.5% of lesions presented within 6 weeks of birth. Intralesional steroid injections were received by 79% of patients. Amblyopia was a definite complication. No local or systemic complications were associated with intralesional steroid injection. Surgery and laser treatment were reserved for persistent lesions.

Conclusion: Early recognition and prompt treatment with intralesional steroid prevents early occlusion amblyopia, but follow-up and management of refractive amblyopia with glasses and patching is necessary in the longer term. In this series, intralesional steroid proved to be a safe effective treatment.

MeSH terms

  • Amblyopia / prevention & control
  • Dexamethasone / therapeutic use*
  • Eyelid Neoplasms / diagnosis
  • Eyelid Neoplasms / drug therapy*
  • Female
  • Glucocorticoids / therapeutic use*
  • Hemangioma, Capillary / diagnosis
  • Hemangioma, Capillary / drug therapy*
  • Humans
  • Infant
  • Infant, Newborn
  • Injections, Intralesional
  • Male
  • Methylprednisolone / therapeutic use*
  • Orbital Neoplasms / diagnosis
  • Orbital Neoplasms / drug therapy*
  • Retrospective Studies
  • Safety
  • Visual Acuity

Substances

  • Glucocorticoids
  • Dexamethasone
  • Methylprednisolone