Effect of constituting amino acid residue numbers on molecularly imprinted chiral recognition sites

Chirality. 2003 Jun;15(6):498-503. doi: 10.1002/chir.10232.

Abstract

In the present study, the effect of constituting amino acid residue numbers of oligopeptide derivatives, which are candidate materials to construct molecular recognition sites, on chiral recognition ability was investigated. Chiral recognition sites were formed from oligopeptide derivatives, of which constituting amino acid residue numbers were three to six, by adopting an alternative molecular imprinting. It was made clear that the number four, in other words, the tetrapeptide derivative, is the best candidate material to form a chiral recognition site.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acids / chemistry*
  • Molecular Conformation
  • Oligopeptides / chemistry*
  • Stereoisomerism
  • Tryptophan / chemistry

Substances

  • Amino Acids
  • Oligopeptides
  • Tryptophan