We report electroencephalographic findings in an anesthetized 4-month-old female drug-naive tiger (Tiger felis) affected by partial seizures with secondary generalization. Both clinical signs and electroencephalographic abnormalities were consistent with a forebrain lesion. Recurring epileptiform activity was noted in the left frontal, central and temporal derivations upon visual inspection of the electroencephalogram (EEG). A quantified EEG, displayed on brain maps, showed the predominance of delta and theta slow rhythms. As regards the absolute power, a prevalence of left frontal-temporal activity was noted. An infectious or inflammatory condition was thought to be the most probable cause of the symptomatic epilepsy in our patient. Unfortunately, other differential diagnoses could not be ruled out.