Abstract
Trehalose is a disaccharide that was initially thought to be rare in plants but now appears to be ubiquitous. A recent study has established that the initial step in trehalose synthesis is essential in Arabidopsis. Evidence is emerging that the precursor of trehalose (trehalose-6-phosphate) is an important regulatory molecule. In yeast, trehalose-6-phosphate regulates sugar influx into glycolysis. In plants, trehalose-6-phosphate also appears to regulate sugar metabolism, but the underlying mechanism is unresolved and may be substantially different from that in yeast.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Carbohydrate Metabolism
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Gene Expression Regulation, Enzymologic
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Glucosyltransferases / chemistry
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Glucosyltransferases / genetics
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Glucosyltransferases / metabolism
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Glycolysis / genetics
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Glycolysis / physiology
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Molecular Conformation
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Plants / enzymology*
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Plants / genetics
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Saccharomyces cerevisiae / metabolism
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Seeds / enzymology
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Seeds / genetics
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Sugar Phosphates / metabolism*
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Trehalose / analogs & derivatives*
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Trehalose / metabolism*
Substances
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Sugar Phosphates
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trehalose-6-phosphate
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Trehalose
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Glucosyltransferases
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trehalose-6-phosphate synthase