This study investigated the bias introduced by an inlet sampling line on a respirable mass monitor. The 1.5-m electrically conductive, flexible sampling line conducts aerosol at a flow rate of 2.2 Lpm from a helmet-mounted inlet to a waist-mounted sensor for mass concentration measurement. Particulate transport was modeled for each section of the sampling line and considered the effects of diffusion, gravitational settling, and inertial impaction. An estimate of respirable mass concentration measured with the sampling line was determined by integrating assumed workplace aerosols with the transport curves. The bias introduced by the sampling line was then calculated by dividing the difference between the respirable mass concentration with and without the sampling line by that without the sampling line. For the current sampling line, in which the inner diameter is 4.83 mm, bias was calculated as -0.3 percent, -2.4 percent, -4.6 percent, and -6.7 percent for four test aerosols with mass median aerodynamic diameters of 0.6 microm, 4 microm, 12 microm, and 30 microm, respectively. Optimization studies suggest that increasing the sampling line with a larger inner diameter by a factor of 1.25 to 1.75 will minimize bias to below -3.0 percent. An experimental study confirmed that bias due to the presence of the sampling line is small.