Clinically significant liver disease is probably a rare condition in Turner's syndrome and only a few cases of severe liver disease have been described. The natural history of patients with Turner's syndrome and elevated cholestatic liver enzymes is unclear. We report a case with a long history of intrahepatic cholestasis and without clinical or histopathological progression in 12 years of follow-up. Like some other reports our case suggests, also histologically, that the liver disease in these patients runs a benign course.
Copyright 2003 S. Karger AG, Basel