Maternal total parenteral nutrition and fetal subdural hematoma

Obstet Gynecol. 2003 May;101(5 Pt 2):1142-4. doi: 10.1016/s0029-7844(02)02622-4.

Abstract

Background: Fetal subdural hematoma is rare, and no case resulting from vitamin K deficiency secondary to maternal total parenteral nutrition has been reported.

Case: A 28-year-old woman was managed with total parenteral nutrition from 28 weeks' gestation because of continuous vomiting due to esophageal hiatal hernia. A sinusoidal pattern by cardiotocogram was observed at 31 weeks' gestation. Serial sonograms showed a fetal subdural hematoma, and cesarean delivery was performed. Although the maternal hepaplastin test result was normal and the maternal PIVKA-II concentration was only slightly elevated, the neonate was severely anemic and had severe vitamin K deficiency.

Conclusion: Severe fetal vitamin K deficiency can develop even when the maternal deficiency is mild. When maternal total parenteral nutrition is necessary, supplemental vitamin K should be administered.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Fetal Diseases / diagnostic imaging*
  • Fetal Diseases / etiology*
  • Hematoma, Subdural / diagnostic imaging*
  • Hematoma, Subdural / etiology*
  • Hernia, Hiatal / therapy*
  • Humans
  • Parenteral Nutrition, Total*
  • Pregnancy
  • Pregnancy Complications / therapy*
  • Pregnancy Trimester, Third
  • Ultrasonography, Prenatal
  • Vitamin K Deficiency / complications*