Complete revascularization in patients with severe left ventricular dysfunction

Ann Thorac Cardiovasc Surg. 2003 Apr;9(2):111-6.

Abstract

Objective: This study evaluates whether patients with coronary artery disease and severely depressed left ventricular ejection fraction (LVEF) benefit from complete revascularization by multivessel coronary artery bypass.

Methods: From April 1994 to May 2002, 42 patients who underwent coronary artery bypass grafting (CABG) at our institution had impaired left ventricular (LV) function [an ejection fraction (EF) of 30% or less]. The average preoperative LVEF was 23.8%. The mean number of grafts was 4.6. Complete revascularization by multivessel bypass grafting was the goal for all patients.

Results: Thirty days mortality was 0 and hospital mortality was 2.4%. The mean graft patency rate for 35 (83%) patients at one month was 98.8%. The mean postoperative LVEF improved significantly, from 23.8% to 35.2% (p<0.05), and the New York Heart Association (NYHA) classification was improved in most patients. The Kaplan-Meier estimate of survival at 5 years was 83.1%, and that of the cardiac event-free rate at 5 years was 77.5%.

Conclusion: For patients with poor LV function, complete surgical revascularization by multivessel bypass grafting can be performed safely, with satisfactory hospital mortality and long-term results.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Coronary Artery Bypass*
  • Coronary Disease / complications
  • Coronary Disease / surgery*
  • Female
  • Heart Failure / complications
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications
  • Stroke Volume
  • Vascular Patency
  • Ventricular Dysfunction, Left / complications*
  • Ventricular Dysfunction, Left / physiopathology