Abstract
Wedelolactone (WL) and demethylwedelolactone (DWL) isolated from Eclipta alba were tested in the trypsin inhibition bioassay (in vitro). Both compounds showed potent activity. IC(50) values of WL and DWL were found to be 2.9 and 3.0 microg/mL respectively.
Copyright 2003 John Wiley & Sons, Ltd.
MeSH terms
-
Animals
-
Chickens
-
Coumarins / pharmacology*
-
Eclipta*
-
Humans
-
Inhibitory Concentration 50
-
Ovum / drug effects
-
Phytotherapy*
-
Plant Extracts / pharmacology
-
Protease Inhibitors / pharmacology*
-
Trypsin / drug effects*
Substances
-
Coumarins
-
Plant Extracts
-
Protease Inhibitors
-
wedelolactone
-
demethylwedelolactone
-
Trypsin