Essential oil composition and antifungal activity of Foeniculum vulgare Mill obtained by different distillation conditions

Phytother Res. 2003 Apr;17(4):368-71. doi: 10.1002/ptr.1159.

Abstract

The influence of different hydrodistillation conditions was evaluated from the standpoint of essential oil yield, chemical composition and antifungal activity from seeds of Foeniculum vulgare Mill. Three hydrodistillation conditions were considered. The main constituents of the oils were: (E)-anethole (72.27%-74.18%), fenchone (11.32%-16.35%) and methyl chavicol (3.78%-5.29%). The method of distillation significantly effected the essential oil yield and quantitative composition, although the antifungal activity of the oils against some fungi was only slightly altered.

MeSH terms

  • Antifungal Agents / administration & dosage
  • Antifungal Agents / chemistry
  • Antifungal Agents / pharmacology*
  • Antifungal Agents / therapeutic use
  • Foeniculum*
  • Fungi / drug effects*
  • Humans
  • Microbial Sensitivity Tests
  • Phytotherapy*
  • Plant Oils / administration & dosage
  • Plant Oils / chemistry
  • Plant Oils / pharmacology*
  • Plant Oils / therapeutic use
  • Seeds
  • Structure-Activity Relationship

Substances

  • Antifungal Agents
  • Plant Oils