The scheme of the complex microbiological diagnostics of cholera, dysentery, salmonellosis and escherichiosis has been developed. The scheme includes the introduction of material taken from a patient with acute enteric infection into 1% peptone water (pH 8.0), followed by inoculation into Endo medium (pH 7.4-8.0) and the selection of colonies on MC-agar with the subsequent final identification of bacteria with the use of biochemical, serological and genetic methods of investigation. This scheme is proposed for use in bacteriological sections of specialized antiepidemic brigades working on the liquidation of the consequences of emergency situations when the epidemiological safety of the population is threatened.