Abstract
CHARACTERISTICS OF THE RENAL DAMAGE: Type I cryoglobulinemia, composed of a single monoclonal immunoglobulin, may be responsible for a glomerulopathy with clinical presentation and histological characteristics close to those of mixed cryoglobulinemia.
Context:
Type I cryoglobulins complicate a malignant haematological disease, chronic lymphoid leukaemia or non-Hodgkin's malignant lymphoma in 60% of cases.
Evolution:
Treatment with corticosteroids and immunosuppressors or antimitotics often leads to the parallel stabilisation or remission of the renal manifestations and the haematological disease
Publication types
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Comparative Study
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English Abstract
MeSH terms
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Acute Disease
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Adrenal Cortex Hormones / therapeutic use
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Animals
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Biopsy
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Cryoglobulinemia / classification
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Cryoglobulinemia / complications*
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Cryoglobulinemia / immunology
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Female
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Hepatitis C / complications
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Hepatitis C / immunology
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Humans
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Immunoglobulins / immunology
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Immunosuppressive Agents / therapeutic use
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Kidney / pathology
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Kidney Diseases / etiology*
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Kidney Diseases / immunology
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Kidney Diseases / pathology
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Kidney Diseases / therapy
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Male
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Mice
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Mice, Inbred BALB C
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Middle Aged
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Multicenter Studies as Topic
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Nephritis / etiology
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Nephritis / immunology
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Nephritis / pathology
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Nephritis / therapy
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Nephrotic Syndrome / etiology
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Nephrotic Syndrome / immunology
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Nephrotic Syndrome / pathology
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Nephrotic Syndrome / therapy
Substances
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Adrenal Cortex Hormones
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Immunoglobulins
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Immunosuppressive Agents