Biological efficacy of electroless-deposited silver on plasma activated polyurethane

J E Gray; P R Norton; R Alnouno; C L Marolda; M A Valvano; K Griffiths

doi:10.1016/s0142-9612(03)00057-7

Biological efficacy of electroless-deposited silver on plasma activated polyurethane

Biomaterials. 2003 Jul;24(16):2759-65. doi: 10.1016/s0142-9612(03)00057-7.

Authors

J E Gray¹, P R Norton, R Alnouno, C L Marolda, M A Valvano, K Griffiths

Affiliation

¹ Department of Chemistry and Interface Science Western, University of Western Ontario, London, Ontario, Canada N6A 5B7.

PMID: 12711522
DOI: 10.1016/s0142-9612(03)00057-7

Abstract

Silver coating of catheters has been shown to have inhibitory effects on bacterial growth and adhesion to catheter surfaces. In this study, plasma-modification was used to enhance the adhesion of an electroless silver coating on polyurethane. Both the antibacterial and antiadhesive properties of these coatings were investigated. Bacterial growth was inhibited in cultures exposed to silver-treated polyurethane compared to unmodified polyurethane. Higher growth inhibition was observed for polyurethane surfaces with lower silver coverage. Bacterial adhesion was completely inhibited on all silver-coated surfaces.

Publication types

Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / pharmacology
Bacterial Adhesion / drug effects*
Bacterial Adhesion / physiology
Coated Materials, Biocompatible / chemical synthesis
Coated Materials, Biocompatible / pharmacology*
Electrochemistry / methods
Escherichia coli / cytology*
Escherichia coli / drug effects*
Escherichia coli / growth & development
Hot Temperature*
Materials Testing
Polyurethanes*
Prosthesis-Related Infections / prevention & control
Silver / pharmacology*
Surface Properties

Substances

Anti-Bacterial Agents
Coated Materials, Biocompatible
Polyurethanes
Silver