Antifungal and antioxidant compounds from the root bark of Fagara zanthoxyloides

Planta Med. 2003 Apr;69(4):316-20. doi: 10.1055/s-2003-38877.

Abstract

Phytochemical investigation of the CH 2 Cl 2 extract of Fagara zanthoxyloides Lam. (Rutaceae) led to the isolation of eleven compounds. One phenylethanoid derivative is a new natural product. The isolation of the antifungal and the antioxidant compounds was monitored by direct TLC bioautographic assays. The structures of the isolated compounds were elucidated by classical spectroscopic methods including UV, NMR, MS and HR-MS.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents
  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / pharmacology*
  • Antifungal Agents / chemistry
  • Antifungal Agents / pharmacology*
  • Antioxidants / chemistry
  • Antioxidants / pharmacology*
  • Bacillus subtilis / drug effects
  • Biphenyl Compounds
  • Candida albicans / drug effects
  • Cladosporium / drug effects
  • Humans
  • Microbial Sensitivity Tests
  • Phytotherapy*
  • Picrates
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology*
  • Plant Roots
  • Zanthoxylum*

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antifungal Agents
  • Antioxidants
  • Biphenyl Compounds
  • Picrates
  • Plant Extracts
  • 1,1-diphenyl-2-picrylhydrazyl