Comparison of automated ACMIA and EMIT immunoassays for whole blood cyclosporin monitoring

Clin Lab. 2003;49(3-4):135-40.

Abstract

Objective: Evaluation of a new fully automated antibody conjugated magnetic immunoassay (ACMIA) for whole blood cyclosporin (CsA) monitoring.

Method: Evaluation of the analytical performance of the ACMIA method and comparison to the Enzyme Multiplied Immunoassay (EMIT) method.

Results: The analytical performance of the ACMIA and the EMIT methods was comparable. Without the need of a pretreatment step of the sample, the ACMIA method is faster than the EMIT method.

Conclusion: The ACMIA method for CsA monitoring is a good alternative to the EMIT method.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Cyclosporine / blood*
  • Cyclosporine / immunology
  • Enzyme Multiplied Immunoassay Technique
  • Humans
  • Immunoassay / instrumentation
  • Immunoassay / methods*

Substances

  • Cyclosporine