Abstract
Electron spin resonance and fluorescence in situ hybridization were used to evaluate the dose to the finger of a worker who accidentally touched a radiotherapy 60Co therapy source in November 1995. In September 1999, the middle finger was amputated. We estimated the dose to the bone of the finger to be 6.4 +/- 0.5 Gy using the electron spin resonance additive dose method and a corrected dose of about 20 +/- 3 Gy could be inferred by translocation analysis in peripheral lymphocytes using the fluorescence in situ hybridization method. This retrospective dosimetry was performed for the victim 4 y after the accident, but the compatibility of the results obtained by physical and biological methods reinforce their validity, although in the case of partial-body exposure the biological method has limitations and demonstrates the need to find appropriate correction factors.
Publication types
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Case Reports
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Comparative Study
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Evaluation Study
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Research Support, Non-U.S. Gov't
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Validation Study
MeSH terms
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Adult
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Amputation, Surgical
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Bones of Upper Extremity / chemistry
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Bones of Upper Extremity / radiation effects*
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Cells, Cultured
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Cobalt Radioisotopes / adverse effects*
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Electron Spin Resonance Spectroscopy / methods
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Finger Injuries / etiology
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Fingers / radiation effects*
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Fingers / surgery
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Follow-Up Studies
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Health Personnel
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Humans
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In Situ Hybridization, Fluorescence / methods
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In Vitro Techniques
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Lymphocytes / blood
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Lymphocytes / pathology
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Lymphocytes / radiation effects
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Male
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Occupational Exposure / analysis*
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Radiation Injuries / etiology
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Radiation Monitoring / instrumentation
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Radiation Monitoring / methods*
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Radioactive Hazard Release
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Radiometry / methods*
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Retrospective Studies
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Sensitivity and Specificity
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Translocation, Genetic / radiation effects