Evaluation of a high dose to a finger from a 60Co accident

Health Phys. 2003 Apr;84(4):477-82. doi: 10.1097/00004032-200304000-00007.

Abstract

Electron spin resonance and fluorescence in situ hybridization were used to evaluate the dose to the finger of a worker who accidentally touched a radiotherapy 60Co therapy source in November 1995. In September 1999, the middle finger was amputated. We estimated the dose to the bone of the finger to be 6.4 +/- 0.5 Gy using the electron spin resonance additive dose method and a corrected dose of about 20 +/- 3 Gy could be inferred by translocation analysis in peripheral lymphocytes using the fluorescence in situ hybridization method. This retrospective dosimetry was performed for the victim 4 y after the accident, but the compatibility of the results obtained by physical and biological methods reinforce their validity, although in the case of partial-body exposure the biological method has limitations and demonstrates the need to find appropriate correction factors.

Publication types

  • Case Reports
  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Adult
  • Amputation, Surgical
  • Bones of Upper Extremity / chemistry
  • Bones of Upper Extremity / radiation effects*
  • Cells, Cultured
  • Cobalt Radioisotopes / adverse effects*
  • Electron Spin Resonance Spectroscopy / methods
  • Finger Injuries / etiology
  • Fingers / radiation effects*
  • Fingers / surgery
  • Follow-Up Studies
  • Health Personnel
  • Humans
  • In Situ Hybridization, Fluorescence / methods
  • In Vitro Techniques
  • Lymphocytes / blood
  • Lymphocytes / pathology
  • Lymphocytes / radiation effects
  • Male
  • Occupational Exposure / analysis*
  • Radiation Injuries / etiology
  • Radiation Monitoring / instrumentation
  • Radiation Monitoring / methods*
  • Radioactive Hazard Release
  • Radiometry / methods*
  • Retrospective Studies
  • Sensitivity and Specificity
  • Translocation, Genetic / radiation effects

Substances

  • Cobalt Radioisotopes