In vitro evaluation of the activity of aromatic nitrocompounds against Trypanosoma cruzi

Mem Inst Oswaldo Cruz. 2003 Jan;98(1):141-4. doi: 10.1590/s0074-02762003000100018. Epub 2003 Apr 9.

Abstract

Fourteen compounds were evaluated for their activity against Trypanosoma cruzi blood stream forms at the concentration of 500 g/ml. Six compounds were active and re-tested at lower concentrations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Drug Evaluation, Preclinical
  • Inhibitory Concentration 50
  • Mice
  • Nitro Compounds / chemistry
  • Nitro Compounds / pharmacology*
  • Trypanosoma cruzi / drug effects*

Substances

  • Nitro Compounds