The mouse (Mus musculus) T cell receptor alpha (TRA) and delta (TRD) variable genes

Nathalie Bosc; Marie-Paule Lefranc

doi:10.1016/s0145-305x(03)00027-2

The mouse (Mus musculus) T cell receptor alpha (TRA) and delta (TRD) variable genes

Dev Comp Immunol. 2003 Jun-Jul;27(6-7):465-97. doi: 10.1016/s0145-305x(03)00027-2.

Authors

Nathalie Bosc¹, Marie-Paule Lefranc

Affiliation

¹ IMGT, Laboratoire d'ImmunoGénétique Moléculaire (LIGM), Université Montpellier II, Institut de Génétique Humaine, UPR CNRS 1142, 141 rue de la Cardonille, 34396 5, Montpellier Cedex, France.

PMID: 12697305
DOI: 10.1016/s0145-305x(03)00027-2

Abstract

'The Mouse (Mus musculus) T cell receptor alpha (TRA) and delta (TRD) variable genes' 'IMGT Locus in Focus' report provides the first complete list of the mouse TRAV and TRDV genes which span 1550 kb on chromosome 14 at 19.7 cM. The total number of TRAV genes per haploid genome is 98 belonging to 23 subgroups. This includes 10 TRAV/DV genes which belong to seven subgroups. The functional TRAV genomic repertoire comprises 72-82 TRAV (including 9-10 TRAV/DV) belonging to 19 subgroups. The total number of TRDV genes per haploid genome is 16 (including the 10 TRAV/DV) belonging to 12 subgroups. The functional TRDV genomic repertoire comprises 14-15 genes (5 TRDV and 9-10 TRAV/DV) belonging to 11-12 subgroups. The eight tables and three figures of this report are available at the IMGT Marie-Paule page of IMGT. The international ImMunoGeneTics information system (http://imgt.cines.fr) created by Marie-Paule Lefranc, Université Montpellier II, CNRS, France.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Animals
Chromosome Mapping
Genes, T-Cell Receptor alpha*
Genes, T-Cell Receptor delta*
Mice
Molecular Sequence Data
Terminology as Topic*