Oral cancer research with an emphasis on genomic analysis

Bull Tokyo Dent Coll. 2002 Nov;43(4):209-22. doi: 10.2209/tdcpublication.43.209.

Abstract

Ablative surgery has been a standard procedure for many years, but during the past few years there has been a significant improvement in our understanding of invasion and metastasis in oral cancer. Each procedure has to be planned individually. Before surgery, every attempt must have been made to arrive at a proper diagnosis, including the exact nature and aggressiveness of the tumor and an analysis of the patient's genetic background. These procedures and the prognosis will be discussed.

Publication types

  • Review

MeSH terms

  • Carcinoma, Squamous Cell / diagnosis
  • Carcinoma, Squamous Cell / epidemiology
  • Carcinoma, Squamous Cell / genetics*
  • Carcinoma, Squamous Cell / therapy
  • DNA, Neoplasm / analysis
  • Female
  • Genes, Tumor Suppressor
  • Humans
  • Incidence
  • Male
  • Mouth Neoplasms / diagnosis
  • Mouth Neoplasms / epidemiology
  • Mouth Neoplasms / genetics*
  • Mouth Neoplasms / therapy
  • Oligonucleotide Array Sequence Analysis
  • Sex Ratio

Substances

  • DNA, Neoplasm