Abstract
Application of the bivalent approach to the cyclopenta[c]thiophene series led to a potent cytotoxic dimer.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents / chemical synthesis*
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / pharmacology*
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Drug Screening Assays, Antitumor
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Humans
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Leukemia / metabolism
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Structure-Activity Relationship
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Thiophenes / chemical synthesis*
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Thiophenes / chemistry
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Thiophenes / pharmacology*
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Tumor Cells, Cultured
Substances
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Antineoplastic Agents
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Thiophenes