The 14th International Symposium on Microsomes and Drug Oxidations was held July 2226, 2002, in Sapporo, Japan. The meeting included 13 plenary sessions, 75 symposia lectures and about 200 poster presentations, and covered a wide variety of topics on general, clinical and toxicologic aspects of drug metabolism. Highlights of the meeting are discussed. (c) 2002 Prous Science. All rights reserved.