Evaluation of two anesthetic techniques for hemodynamic control during carotid surgery. Preliminary results

Minerva Anestesiol. 2003 Jan-Feb;69(1-2):23-9, 29-33.
[Article in English, Italian]

Abstract

Background: To evaluate two anesthetic techniques for hemodynamic control during carotid TEA surgery and early post-surgery.

Methods: Two study groups treated by carotid surgery were compared; the Fentanyl group consisted of 7 patients in ASA class 3, the Remifentanil-Sevoflorane group included 12 patients in ASA class 3. The double product was monitored on entry to the operating room, at 5, 15, 30 min after induction of anesthesia and tracheal intubation, and at 30 min after extubation. Time of extubation, re-awakening and attention levels during early post-surgery, and myocardial ischemia markers were monitored for 48 h after surgery in the Remifentanil group.

Results: Statistical analysis using Student's "t"-test for paired data showed that the double product indicated better hemodynamic stability in the patients who received Remifentanil-Sevoflorane than in those who received Fentanyl.

Conclusions: Compared with anesthesia using Fentanyl and with locoregional techniques, anesthesia with Remifentanil-Sevoflorane in carotid surgery provides a valuable alternative and secures good hemodynamic stability.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Aged
  • Anesthesia*
  • Anesthetics, Inhalation
  • Anesthetics, Intravenous
  • Electrocardiography
  • Electroencephalography
  • Endarterectomy, Carotid* / adverse effects
  • Female
  • Fentanyl
  • Hemodynamics / physiology
  • Humans
  • Intraoperative Period
  • Male
  • Methyl Ethers
  • Myocardial Ischemia / prevention & control
  • Piperidines
  • Remifentanil
  • Risk Factors
  • Sevoflurane
  • Stroke / prevention & control

Substances

  • Anesthetics, Inhalation
  • Anesthetics, Intravenous
  • Methyl Ethers
  • Piperidines
  • Sevoflurane
  • Remifentanil
  • Fentanyl