Glycerol and hyperosmolar nonketotic coma

Am J Ophthalmol. 1976 Apr;81(4):469-72. doi: 10.1016/0002-9394(76)90303-2.

Abstract

Hyperosmolar nonketotic coma occurred in a 29-year-old diabetic man with chronic renal failure after the repeated use of oral glycerol for treatment of acute neovascular glaucoma. Treatment with intravenous hypotonic saline, albumin, and packed red blood cells together with insulin and bicarbonate was successful in overcoming the coma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Albumins / therapeutic use
  • Bicarbonates / therapeutic use
  • Coma / drug therapy*
  • Diuresis
  • Erythrocytes
  • Glaucoma / drug therapy
  • Glycerol / adverse effects
  • Glycerol / therapeutic use*
  • Humans
  • Hypotonic Solutions
  • Insulin / therapeutic use
  • Ketone Bodies / blood*
  • Kidney Failure, Chronic / chemically induced
  • Male
  • Osmolar Concentration
  • Sodium Chloride / therapeutic use

Substances

  • Albumins
  • Bicarbonates
  • Hypotonic Solutions
  • Insulin
  • Ketone Bodies
  • Sodium Chloride
  • Glycerol