KU 70/80 lupus autoantigen is the transcription factor induced by interleukins (IL)-13 and -4 leading to induction of 15-lipoxygenase (15-LO) in human cells

Adv Exp Med Biol. 2002:507:469-81. doi: 10.1007/978-1-4615-0193-0_73.
No abstract available

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antigens, Nuclear / genetics*
  • Arachidonate 15-Lipoxygenase / genetics*
  • Base Sequence
  • DNA Helicases*
  • DNA-Binding Proteins / genetics*
  • Gene Expression Regulation, Enzymologic / drug effects
  • Gene Expression Regulation, Enzymologic / immunology
  • Humans
  • Interleukin-13 / pharmacology*
  • Interleukin-4 / pharmacology*
  • Ku Autoantigen
  • Lung Neoplasms
  • Molecular Sequence Data
  • Mutagenesis, Site-Directed
  • Promoter Regions, Genetic
  • RNA, Messenger / genetics
  • Respiratory Mucosa / drug effects
  • Respiratory Mucosa / immunology
  • Transcription Factors / genetics*
  • Transfection
  • Tumor Cells, Cultured

Substances

  • Antigens, Nuclear
  • DNA-Binding Proteins
  • Interleukin-13
  • RNA, Messenger
  • Transcription Factors
  • Interleukin-4
  • Arachidonate 15-Lipoxygenase
  • DNA Helicases
  • XRCC5 protein, human
  • Xrcc6 protein, human
  • Ku Autoantigen