Cyclooxygenase-2 expression and activity are induced by amyloid-beta 1-42 in brain derived cells

Adv Exp Med Biol. 2002:507:93-9. doi: 10.1007/978-1-4615-0193-0_15.

Authors

MacKenzie Hilfers Bilunas¹, Steven A Moore

Affiliation

¹ Department of Pathology, University of Iowa, 1046 Medical Laboratories, Iowa City, IA 52242, USA.

PMID: 12664570
DOI: 10.1007/978-1-4615-0193-0_15

No abstract available

MeSH terms

Amyloid beta-Peptides / pharmacology*
Animals
Animals, Newborn
Astrocytes / cytology
Astrocytes / drug effects
Astrocytes / enzymology*
Brain / enzymology*
Cell Culture Techniques / methods
Cells, Cultured
Cerebrovascular Circulation / drug effects
Cerebrovascular Circulation / physiology*
Cyclooxygenase 2
Enzyme Induction / drug effects
Gene Expression Regulation, Enzymologic / drug effects
Isoenzymes / genetics*
Mice
Nitric Oxide Synthase / genetics
Nitric Oxide Synthase Type II
Peptide Fragments / pharmacology*
Prostaglandin-Endoperoxide Synthases / genetics*

Substances

Amyloid beta-Peptides
Isoenzymes
Peptide Fragments
amyloid beta-protein (1-42)
Nitric Oxide Synthase
Nitric Oxide Synthase Type II
Nos2 protein, mouse
Cyclooxygenase 2
Prostaglandin-Endoperoxide Synthases