Microabrasion versus microabrasion followed by 15% trichloroacetic acid for treatment of cutaneous hyperpigmentations in adult females

Dermatol Surg. 2003 Apr;29(4):352-6; discussion 356. doi: 10.1046/j.1524-4725.2003.29084.x.

Abstract

Background: Cutaneous hyperpigmentations are common skin disorders that are often refractory to currently available treatments.

Objective: To evaluate the efficacy of microabrasion alone or microabrasion with 15% trichloroacetic acid (TCA) for treatment of cutaneous hyperpigmentations.

Methods: Twenty female patients were treated with microabrasion alone every 2 weeks (group 1), and 20 female patients were treated with microabrasion and application of 15% TCA every 3 weeks (group 2). All patients underwent up to eight treatments. The overall duration of treatment ranged from 2 to 4 months.

Results: In group 1, a complete remission was observed in 8 of 20 cases (40%), partial remission in 10 of 20 cases (50%), and no remission in 2 of 20 cases (10%). In group 2, a complete remission was observed in 10 of 20 cases (50%), a partial remission in 8 of 20 cases (40%), and no remission in 2 of 20 cases (10%). No unexpected or serious side effects were observed in either group.

Conclusions: Microabrasion alone or microabrasion with 15% TCA is an effective, well-tolerated treatment for cutaneous hyperpigmentations.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Dermabrasion / methods*
  • Female
  • Humans
  • Hyperpigmentation / therapy*
  • Middle Aged
  • Treatment Outcome
  • Trichloroacetic Acid / administration & dosage*

Substances

  • Trichloroacetic Acid