[Digestive pathology in children infected with the human immunodeficiency virus (HIV), in Santiago de Chile]

Rev Med Chil. 2003 Jan;131(1):19-24.
[Article in Spanish]

Abstract

Background: Human immunodeficiency virus (HIV) epidemiology has changed, affecting an increasing number of children. As in adults, the disease predominantly affects the digestive and respiratory systems.

Aim: To report the gastrointestinal problems in HIV infected pediatric patients.

Patients and methods: Twenty four HIV infected children (nine male, aged 1 to 12 years old, followed for 1 to 170 months), are reported. This group has been under care by a multiprofessional team.

Results: Oral candidiasis was present in 21 (88%), esophagic candidiasis in 3 (13%), oral ulcers in 4 (17%). Diarrhea was observed in 18 children (75%) and in eight, it had a chronic evolution. Cryptosporidium parvum was the most frequent agent found in six cases (1 with acute and 5 with chronic diarrhea). Schlerosing cholangiopathy was observed in one case, with a fatal outcome, in association to microsporidiosis. Upper endoscopy was done in 11 patients, demonstrating microscopic inflammatory changes in esophagic, gastric and duodenal epithelia in all.

Conclusions: Digestive problems are common in HIV infected pediatric patients. They must be always sought actively. Endoscopy is a valuable tool for the early diagnosis of these problems.

Publication types

  • English Abstract

MeSH terms

  • AIDS-Related Opportunistic Infections / diagnosis
  • AIDS-Related Opportunistic Infections / etiology*
  • Acquired Immunodeficiency Syndrome / complications*
  • Child
  • Child, Preschool
  • Chile
  • Diarrhea / diagnosis
  • Diarrhea / etiology
  • Female
  • Follow-Up Studies
  • Gastrointestinal Diseases / diagnosis
  • Gastrointestinal Diseases / etiology*
  • HIV Infections / complications
  • Humans
  • Infant
  • Male
  • Mouth Diseases / diagnosis
  • Mouth Diseases / etiology