White-coat hypertension and normotension in the League of Hypertension of the Hospital das Clínicas, FMUSP: prevalence, clinical and demographic characteristics

Arq Bras Cardiol. 2003 Feb;80(2):117-26. doi: 10.1590/s0066-782x2003000200001. Epub 2003 Feb 25.
[Article in English, Portuguese]

Abstract

Objective: To assess the prevalence of white-coat normortension, white-coat hypertension, and white-coat effect.

Methods: We assessed 670 medical records of patients from the League of Hypertension of the Hospital das Clínicas of the Medical School of the University of S o Paulo. White-coat hypertension (blood pressure at the medical office: mean of 3 measurements with the oscillometric device > or = 140 or > or = 90 mmHg, or both, and ambulatory blood pressure monitoring mean during wakefulness < 135/85) and white-coat normotension (office blood pressure < 140/90 and blood pressure during wakefulness on ambulatory blood pressure monitoring > or = 135/85) were analyzed in 183 patients taking no medication. The white-coat effect (difference between office and ambulatory blood pressure > 20 mmHg for systolic and 10 mmHg for diastolic) was analyzed in 487 patients on treatment, 374 of whom underwent multivariate analysis to identify the variables that better explain the white-coat effect.

Results: Prevalence of white-coat normotension was 12%, prevalence of white-coat hypertension was 20%, and prevalence of the white-coat effect was 27%. A significant correlation (p<0.05) was observed between white-coat hypertension and familial history of hypertension, and between the white-coat effect and sex, severity of the office diastolic blood pressure, and thickness of left ventricular posterior wall.

Conclusion: White-coat hypertension, white-coat normotension, and white-coat effect should be considered in the diagnosis of hypertension.

MeSH terms

  • Blood Pressure Determination / methods
  • Blood Pressure*
  • Brazil / epidemiology
  • Female
  • Humans
  • Hypertension / diagnosis
  • Hypertension / drug therapy
  • Hypertension / epidemiology*
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Office Visits*
  • Prevalence
  • Retrospective Studies