Abstract
Neovir, an inductor of interferon-alpha, was injected intramuscularly to 15 male patients aged 16-44 years with diagnosed acute viral hepatitis in a dose of 250 mg a day, 2-3 times a week, for 3 months. By the end of the therapy hepatitis C virus RNA could still be isolated in 84.6% of the patients; the values of AlaT, AsaT and alkaline phosphatase exceeded the normal levels twofold. The result of the therapy is regarded as ineffective.
Publication types
-
Clinical Trial
-
English Abstract
MeSH terms
-
Acridines / therapeutic use*
-
Acute Disease
-
Adolescent
-
Adult
-
Alanine Transaminase / blood
-
Alkaline Phosphatase / blood
-
Aspartate Aminotransferases / blood
-
Biomarkers / blood
-
Drug Administration Schedule
-
Hepacivirus / isolation & purification
-
Hepatitis C / blood
-
Hepatitis C / drug therapy*
-
Hepatitis C / virology
-
Humans
-
Injections, Intramuscular
-
Interferon Inducers / therapeutic use*
-
Male
-
RNA, Viral / analysis
-
Treatment Outcome
-
Viral Load
Substances
-
Acridines
-
Biomarkers
-
Interferon Inducers
-
RNA, Viral
-
Camedon
-
Aspartate Aminotransferases
-
Alanine Transaminase
-
Alkaline Phosphatase