Nutritional deficiencies in German middle-class male alcohol consumers: relation to dietary intake and severity of liver disease

Eur J Clin Nutr. 2003 Mar;57(3):431-8. doi: 10.1038/sj.ejcn.1601557.

Abstract

Objective: The purpose of the present study was to compare the nutrient intake and the nutritional status between German middle-class alcohol consumers and non-drinkers.

Design: Cross-sectional study using patients with different stages of alcoholic liver disease (ALD) and healthy volunteers.

Setting: Southern Germany.

Subjects: Seventy-six hospitalized German middle-class alcohol consumers with different stages of alcoholic liver disease (ALD) and 22 healthy control subjects.

Methods: Subjects and controls were nutritionally assessed and mineral and vitamin content was measured in blood and urine.

Results: When compared with controls, alcohol consumers had significantly higher intakes of total calories, but intake of non-alcoholic calories did not differ between groups (P<0.05). Among drinkers, there was a decrease in percentage of energy derived from protein and fat and a significant increase in carbohydrates (P<0.05). With the exception of vitamin E, micronutrient intake of alcoholics was equal to that of controls; however, blood vitamin (vitamin C, retinol, lycopene, alpha- and gamma-carotene) and trace element (selenium, zinc) concentrations of alcohol-drinking patients were lower than those of non-drinkers.

Conclusion: From the results of this study it is concluded that in German middle-class male alcohol consumers the status of several micronutrients is disturbed, although dietary intake hardly differs from that in non-alcoholic controls.

MeSH terms

  • Adult
  • Alcohol Drinking*
  • Case-Control Studies
  • Cross-Sectional Studies
  • Energy Intake
  • Germany
  • Humans
  • Liver Diseases, Alcoholic / blood*
  • Liver Diseases, Alcoholic / complications
  • Liver Diseases, Alcoholic / urine*
  • Male
  • Middle Aged
  • Minerals* / administration & dosage
  • Minerals* / blood
  • Minerals* / urine
  • Nutrition Disorders / blood
  • Nutrition Disorders / etiology
  • Nutrition Disorders / urine
  • Nutritional Status*
  • Selenium / blood
  • Selenium / urine
  • Severity of Illness Index
  • Vitamins* / administration & dosage
  • Vitamins* / blood
  • Vitamins* / urine
  • Zinc / blood
  • Zinc / urine

Substances

  • Minerals
  • Vitamins
  • Selenium
  • Zinc