Nanotechnological approaches for the delivery of macromolecules

J Control Release. 2003 Feb 21;87(1-3):81-8. doi: 10.1016/s0168-3659(03)00014-2.

Abstract

In this overview, novel approaches are described for the controlled release and/or for the targeted delivery of macromolecules such as proteins and DNA. The building stones of these highly complex systems are (phospho)lipids and/or (biodegradable) polymers. They should be carefully chosen and preparation protocols should be rationally designed to maximize chances for success.

Publication types

  • Review

MeSH terms

  • Animals
  • Drug Delivery Systems / methods*
  • Humans
  • Macromolecular Substances*
  • Nanotechnology / methods*

Substances

  • Macromolecular Substances