Work, salt intake and the development of stomach cancer

Med Hypotheses. 2003 Apr;60(4):552-6. doi: 10.1016/s0306-9877(03)00014-8.

Abstract

An excess of stomach cancer among workers has been observed and it could be argued that men whose occupation involves heavy work eat more and are consequently exposed to a greater quantity of carcinogens in their food. Working under conditions of heat stress greatly increases a worker's salt excretion by as much as 0.1-15.0 g through sweating during one shift of work. Workers exposed to heat stress had consumed daily as much as from 13.0 to 38.0 g of salt, which is much higher than the safe level of 6 g/person/day recommended by the WHO, to keep a balance of salt in the body. Because salt strongly enhances and promotes chemical gastric carcinogenesis and Helicobacter pylori infection in both humans and animals, there is an association between work, salt intake, and the development of stomach cancer among workers in particular and in humans in general.

MeSH terms

  • Animals
  • Carcinogens
  • Hot Temperature
  • Humans
  • Models, Theoretical
  • Sodium Chloride / adverse effects*
  • Stomach Neoplasms / etiology*
  • Sweat
  • Temperature
  • Time Factors
  • Work

Substances

  • Carcinogens
  • Sodium Chloride