[Rapid identification of pneumococcal antigenes in urines by the Now Streptococcus pneumoniae Binax test]

Ann Biol Clin (Paris). 2003 Jan-Feb;61(1):106-9.
[Article in French]

Abstract

Streptococcus pneumoniae is responsible for many infectious conditions but probably with an underestimated incidence especially because of the fragility of the bacteria. The present study has evaluated a new test which detects a pneumococcal antigen in urine (Now S.p Binax). Urine samples from 181 children and 40 adults have been tested. All the patients presented with typical clinical signs of pneumococcal infection. Sensitivity = 91.7 %; specificity = 54.2 %; positive predictive value = 50 %; and negative predictive value = 92.9 % have been observed. Although the sensitivity and specificity were lower than those announced by the manufacturer, the test is easy to handle and provides a rapid argument for the diagnosis of pneumococcal infection, especially in the case of invasive infections like meningitis and bacteraemia.

Publication types

  • English Abstract

MeSH terms

  • Antigens, Bacterial / urine*
  • False Negative Reactions
  • False Positive Reactions
  • Humans
  • Pneumococcal Infections / diagnosis*
  • Pneumococcal Infections / urine*
  • Reproducibility of Results
  • Streptococcus pneumoniae / isolation & purification*

Substances

  • Antigens, Bacterial