A preliminary morphometric magnetic resonance imaging study of regional brain volumes in body dysmorphic disorder

Scott L Rauch; Katharine A Phillips; Ethan Segal; Nikos Makris; Lisa M Shin; Paul J Whalen; Michael A Jenike; Verne S Caviness Jr; David N Kennedy

doi:10.1016/s0925-4927(02)00117-8

A preliminary morphometric magnetic resonance imaging study of regional brain volumes in body dysmorphic disorder

Psychiatry Res. 2003 Jan 20;122(1):13-9. doi: 10.1016/s0925-4927(02)00117-8.

Authors

Scott L Rauch¹, Katharine A Phillips, Ethan Segal, Nikos Makris, Lisa M Shin, Paul J Whalen, Michael A Jenike, Verne S Caviness Jr, David N Kennedy

Affiliation

¹ Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Building 149, 139th Street, 9th Floor, Charlestown, MA 02129, USA. rauch@psych.mgh.harvard.edu

PMID: 12589879
DOI: 10.1016/s0925-4927(02)00117-8

Abstract

Morphometric magnetic resonance imaging (MRI) was used to compare regional brain volumes in eight women with body dysmorphic disorder (BDD) and eight healthy comparison subjects. The BDD group exhibited a relative leftward shift in caudate asymmetry and greater total white matter vs. the comparison group. Findings with respect to the caudate nucleus are consistent with both the conceptualization of BDD as an obsessive-compulsive spectrum disorder, and the 'striatal topography model' of obsessive-compulsive disorders.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Brain / anatomy & histology*
Female
Functional Laterality / physiology
Humans
Magnetic Resonance Imaging*
Somatoform Disorders / psychology*

Abstract

Publication types

MeSH terms

Grants and funding