Aim: To look for new active constituents from the aerial part of Cimicifuga foetida L.
Methods: Various column chromatographic techniques were used for the isolation and purification of the ingredients. The structure were elucidated on the basis of spectral evidences and chemical reaction.
Results: Five compounds were obtained and identified as 23-O-acetylshengmanol-3-O-alpha-L-arabinopyranoside (1), 23-O-acetylshengmanol-3-O-beta-D-xylopyranoside (2), 25-anhydrocimigenol-3-O-beta-D-xylopyranoside (3), cimigenol-3-O-alpha-L-arabinopyranoside (4), cimigenol-3-O-beta-D-xylopyranoside (5).
Conclusion: Compound 1 is a new compound, and compounds 2 and 4 were isolated from this plant for the first time.