[Studies on the glycoconjugates and glycans from Lycium barbarum L in inhibiting low density lipoprotein (LDL) peroxidation]

Yao Xue Xue Bao. 2001 Feb;36(2):108-11.
[Article in Chinese]

Abstract

Aim: To determine the effects of glycoconjugates and their glycans from Lycium barbarum L. on inhibiting low density lipoprotein (LDL) peroxidation.

Methods: Using Cu(2+)-induced oxidation as a model, the oxidative production of thiobarbituric acid-reactive substances (TBARS) and the LDL electrophoresis migration on agarose gel were measured.

Results: The effects of glycoconjugates and their glycans from Lycium barbarum L. on inhibiting LDL peroxidation were different, among them, glycoconjugate LbGp5 showed the best effect on inhibiting LDL peroxidation.

Conclusion: The glycoconjugates can inhibit LDL peroxidatin while their glycans showed no effects on inhibiting LDL peroxidation.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Fruit / chemistry
  • Glycoconjugates / isolation & purification
  • Glycoconjugates / pharmacology*
  • Humans
  • Lipid Peroxidation / drug effects*
  • Lipoproteins, LDL / metabolism*
  • Lycium / chemistry*
  • Polysaccharides / isolation & purification
  • Polysaccharides / pharmacology

Substances

  • Glycoconjugates
  • Lipoproteins, LDL
  • Polysaccharides