Abstract
Huai-shan-yao (Chinese yam; Rhizome Dioscoreae) is a common food in China. In the present study, we evaluated the protective effects of the crude extract of huai-shan-yao on acute kidney and liver injuries in rats induced by ethanol. Results of pharmacological, biochemical and pathologic observations all showed that rats treated with the extract of huai-shan-yao had decreased damage in renal tubules as well as decreased inflammation in the central vein and necrosis in the liver tissue.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antioxidants / pharmacology
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Central Nervous System Depressants / toxicity
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Dioscorea / chemistry*
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Drugs, Chinese Herbal / pharmacology*
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Ethanol / toxicity
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Kidney / pathology
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Kidney Diseases / chemically induced
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Kidney Diseases / pathology
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Kidney Diseases / prevention & control*
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Kidney Function Tests
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Liver / pathology
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Liver Diseases, Alcoholic / pathology
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Liver Diseases, Alcoholic / prevention & control*
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Liver Function Tests
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Male
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Plant Extracts / pharmacology
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Plant Roots / chemistry
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Rats
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Rats, Wistar
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Silymarin / pharmacology
Substances
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Antioxidants
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Central Nervous System Depressants
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Drugs, Chinese Herbal
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Plant Extracts
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Silymarin
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huai-shan-yao
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Ethanol