Distal ureteral stenosis after early adjuvant intravesical mitomycin C application for superficial bladder cancer

Urol Int. 2003;70(1):74-6. doi: 10.1159/000067698.

Abstract

We report a case of distal ureteral stenosis after transurethral resection of a small bladder tumor near the left ureteral orifice and early postoperative mitomycin C instillation for prevention of recurrence. The patient developed late recurrent stenosis of the ureteral orifice with histologic evidence of localized, severe benign inflammatory reaction. The recurrent stenosis was successfully managed by transurethral resection of the scar tissue and ureteric stenting. Although ureteral stenosis does occur after transurethral resection, the severity and time course of the stenosis in this case suggest an influence of the intravesical chemoprophylaxis used.

Publication types

  • Case Reports

MeSH terms

  • Administration, Intravesical
  • Aged
  • Biopsy, Needle
  • Chemotherapy, Adjuvant / adverse effects
  • Cystectomy / methods
  • Female
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry
  • Mitomycin / administration & dosage
  • Mitomycin / adverse effects*
  • Postoperative Period
  • Recurrence
  • Risk Assessment
  • Ureteral Obstruction / chemically induced*
  • Ureteral Obstruction / pathology
  • Urinary Bladder Neoplasms / drug therapy*
  • Urinary Bladder Neoplasms / pathology
  • Urinary Bladder Neoplasms / surgery*

Substances

  • Mitomycin