Increasingly, social workers are called on to demonstrate the efficacy of their interventions and to contribute to knowledge building in the social sciences. Although social workers have a long tradition of practice ethics, less attention has been given to the unique dimensions of research ethics for social workers. A social work model of research ethics would consider how to balance highly valued ethical principles that are individually focused, such as self-determination and nonmalfeasance (the obligation to do no harm), with equally important values that have a collective focus, such as justice and beneficence (the obligation to bring about good). This article reviews current principles guiding research ethics, such as autonomy, beneficence, nonmalfeasance, and justice and provides an outline of the salient issues for social workers as they strive to address individual and collective interests in research endeavors, such as a greater emphasis on the social justice mission and the need to ensure that social justice objectives do not obscure individual rights and freedoms. The article concludes with preliminary recommendations for developing a social work perspective in research ethics.