Abstract
Haemoglobin concentrations and tumour-pO(2) were evaluated pre-therapy in 30 patients with head and neck cancers. Anterior tibialis muscle-pO(2) was additionally measured in 16 of these patients. Tumour-pO(2) was lower in the most anaemic patients (P=0.032) and correlated with muscle-pO(2) (r=0.809, P<0.001). These results suggest that haemoglobin concentration influences tumour-oxygenation.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Biomarkers / analysis
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Cell Respiration
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Female
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Head and Neck Neoplasms / metabolism*
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Head and Neck Neoplasms / pathology*
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Head and Neck Neoplasms / surgery
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Hemoglobins / analysis*
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Humans
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Linear Models
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Male
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Middle Aged
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Muscle, Skeletal / metabolism
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Neoplasm Staging
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Oxygen Consumption / physiology*
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Predictive Value of Tests
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Preoperative Care / methods
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Probability
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Prospective Studies
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Sensitivity and Specificity