Abstract
We have isolated the complete coding region of HLA-B*39 from a Spanish Caucasoid, using a new PCR primer for its 5' untranslated region. The cDNA matched partial genomic sequences of B*3924, an allele whose distribution appears to be restricted to Mediterranean and Arabian Caucasoids. A single amino acid change exclusive to B*3924 (threonine-98) distinguishes it from B*3903.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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5' Untranslated Regions
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Alleles*
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Amino Acid Substitution
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Base Sequence
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Conserved Sequence
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DNA, Complementary / genetics*
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HLA-B Antigens / genetics*
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HLA-B39 Antigen
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Humans
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Mediterranean Region
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Molecular Sequence Data
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Sequence Analysis, DNA
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Spain
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White People / genetics
Substances
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5' Untranslated Regions
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DNA, Complementary
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HLA-B Antigens
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HLA-B*39:24 antigen
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HLA-B39 Antigen