Complementary DNA sequence of the HLA-B*3924 allele

Eur J Immunogenet. 2003 Feb;30(1):11-2. doi: 10.1046/j.1365-2370.2003.00362.x.

Abstract

We have isolated the complete coding region of HLA-B*39 from a Spanish Caucasoid, using a new PCR primer for its 5' untranslated region. The cDNA matched partial genomic sequences of B*3924, an allele whose distribution appears to be restricted to Mediterranean and Arabian Caucasoids. A single amino acid change exclusive to B*3924 (threonine-98) distinguishes it from B*3903.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 5' Untranslated Regions
  • Alleles*
  • Amino Acid Substitution
  • Base Sequence
  • Conserved Sequence
  • DNA, Complementary / genetics*
  • HLA-B Antigens / genetics*
  • HLA-B39 Antigen
  • Humans
  • Mediterranean Region
  • Molecular Sequence Data
  • Sequence Analysis, DNA
  • Spain
  • White People / genetics

Substances

  • 5' Untranslated Regions
  • DNA, Complementary
  • HLA-B Antigens
  • HLA-B*39:24 antigen
  • HLA-B39 Antigen

Associated data

  • GENBANK/AF428252